The small GTPase Ran defines nuclear pore complex asymmetryNuclear pore complexes at the nuclear envelope are asymmetric structures, whereas those in cytoplasmic or nuclear membranes are symmetric. The (a)symmetry of nuclear pore complexes and peripheral nucleoporin composition depend on the surrounding cellular milieu and the nucleotide state of the small GTPase Ran.Nuclear pore complexes at the nuclear envelope are asymmetric structures, whereas those in cytoplasmic or nuclear membranes are symmetric. The (a)symmetry of nuclear pore complexes and peripheral nucleoporin composition depend on the surrounding cellular milieu and the nucleotide state of the small GTPase Ran.Jenny Sachweh, Mandy Börmel, Sven Klumpe, Anja Becker, Reiya Taniguchi, Marta Anna Kubańska, Verena Pintschovius, Eva Kaindl, Jürgen M. Plitzko, Florian Wilfling, Martin Beck, Bernhard Hampoelzhttps://www.cell.com/cell/fulltext/S0092-8674(25)00814-1?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 19, 2025

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