The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodesHuang et al. demonstrate different functional states of tumor-reactive CD8+ T cells in the TdLNs where TCF-1+TOX− CD8+ T cells are bona fide memory T cells and function as the genuine responders to PD-1/PD-L1 ICB.Huang et al. demonstrate different functional states of tumor-reactive CD8+ T cells in the TdLNs where TCF-1+TOX− CD8+ T cells are bona fide memory T cells and function as the genuine responders to PD-1/PD-L1 ICB.Qizhao Huang, Xia Wu, Zhiming Wang, Xiangyu Chen, Lisha Wang, Yijun Lu, Dan Xiong, Qiao Liu, Yuhan Tian, Huayu Lin, Junyi Guo, Shuqiong Wen, Wei Dong, Xiaofan Yang, Yuchen Yuan, Zhengliang Yue, Shun Lei, Qing Wu, Ling Ran, Luoyingzi Xie, Yifei Wang, Leiqiong Gao, Qin Tian, Xinyuan Zhou, Beicheng Sun, Lifan Xu, Zhonghui Tang, Lilin Yehttps://www.cell.com/cell/fulltext/S0092-8674(22)01192-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 8, 2022
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