The need to diversify genomic studies: Insights from Andean highlanders and AmazoniansMore globally diverse perspectives are needed in genomic studies and precision medicine practices on non-Europeans. Here, we illustrate this by discussing the distribution of clinically actionable genetic variants involved in drug response in Andean highlanders and Amazonians, considering their environment, history, genetic structure, and historical biases in the perception of biological diversity of Native Americans.More globally diverse perspectives are needed in genomic studies and precision medicine practices on non-Europeans. Here, we illustrate this by discussing the distribution of clinically actionable genetic variants involved in drug response in Andean highlanders and Amazonians, considering their environment, history, genetic structure, and historical biases in the perception of biological diversity of Native Americans.Isabela Alvim, Carolina Silva-Carvalho, Marla Mendes de Aquino, Victor Borda, Cesar Sanchez, Carlos Padilla, Omar Cáceres, Isabela Rezende-Diniz, Julia Saraiva-Duarte, Lucas Faria-Costa, Meddly L. Santolalla, Fernanda Rodrigues-Soares, Camila Zolini, Adrián Llerena, Timothy D. O’Connor, Robert H. Gilman, Heinner Guio, Eduardo Tarazona-Santoshttps://www.cell.com/cell/fulltext/S0092-8674(24)00769-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 9, 2024

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