TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory FateA subset of B cell lymphomas is driven by mutations that impair plasma cell differentiation and instead bias cell fate toward immature memory B cells, which preferentially re-enter germinal center reactions to drive lymphomagenesis.A subset of B cell lymphomas is driven by mutations that impair plasma cell differentiation and instead bias cell fate toward immature memory B cells, which preferentially re-enter germinal center reactions to drive lymphomagenesis.Leandro Venturutti, Matt Teater, Andrew Zhai, Amy Chadburn, Leena Babiker, Daleum Kim, Wendy Béguelin, Tak C. Lee, Youngjun Kim, Christopher R. Chin, William T. Yewdell, Brian Raught, Jude M. Phillip, Yanwen Jiang, Louis M. Staudt, Michael R. Green, Jayanta Chaudhuri, Olivier Elemento, Pedro Farinha, Andrew P. Weng, Michael D. Nissen, Christian Steidl, Ryan D. Morin, David W. Scott, Gilbert G. Privé, Ari M. Melnickhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2930682-6%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJuly 3, 2020
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