T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

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T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individualsT cells from most SARS-CoV-2 infected and/or vaccinated individuals have preserved reactivity to the Omicron variant and reactivity is enhanced by booster vaccination. However, approximately 20% of individuals have reduced T-cell recognition of the Omicron spike, potentially due to escape of HLA class I-restricted epitopes.T cells from most SARS-CoV-2 infected and/or vaccinated individuals have preserved reactivity to the Omicron variant and reactivity is enhanced by booster vaccination. However, approximately 20% of individuals have reduced T-cell recognition of the Omicron spike, potentially due to escape of HLA class I-restricted epitopes.Vivek Naranbhai, Anusha Nathan, Clarety Kaseke, Cristhian Berrios, Ashok Khatri, Shawn Choi, Matthew A. Getz, Rhoda Tano-Menka, Onosereme Ofoman, Alton Gayton, Fernando Senjobe, Zezhou Zhao, Kerri J. St Denis, Evan C. Lam, Mary Carrington, Wilfredo F. Garcia-Beltran, Alejandro B. Balazs, Bruce D. Walker, A. John Iafrate, Gaurav D. Gaihahttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900140-4%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 3, 2022

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