Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolismThe impact of synonymous mutations remains elusive. Here, the authors demonstrate that synonymous mutations can promote tumorigenesis by disrupting post-transcriptional m6A modification. The findings provide fresh insights into understanding the genotype-phenotype relationship in cancer and beyond.The impact of synonymous mutations remains elusive. Here, the authors demonstrate that synonymous mutations can promote tumorigenesis by disrupting post-transcriptional m6A modification. The findings provide fresh insights into understanding the genotype-phenotype relationship in cancer and beyond.Yiheng Lan, Zhen Xia, Qizhe Shao, Peng Lin, Jinhong Lu, Xiaoying Xiao, Mengyue Zheng, Di Chen, Yanmei Dou, Qi Xiehttps://www.cell.com/cell/fulltext/S0092-8674(25)00095-9?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 14, 2025

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