Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion
Structural Basis of WLS/Evi-Mediated Wnt Transport and SecretionThe cryo-EM structure of palmitoleated human WNT8A bound to its transporter Wntless/WLS/Evi uncovers the mechanisms of Wnt secretion, revealing broad structural similarities to GPCRs and lipid-sensing pathways.The cryo-EM structure of palmitoleated human WNT8A bound to its transporter Wntless/WLS/Evi uncovers the mechanisms of Wnt secretion, revealing broad structural similarities to GPCRs and lipid-sensing pathways.Rie Nygaard, Jia Yu, Jonathan Kim, Daniel R. Ross, Giacomo Parisi, Oliver B. Clarke, David M. Virshup, Filippo Manciahttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2931610-X%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 24, 2020
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