Squeeze pumping of lipids and insecticides by ABCH transporter
Squeeze pumping of lipids and insecticides by ABCH transporterHigh-resolution cryo-EM structures and biochemical data reveal the dynamic process by which the ABCH transporter binds and transports lipid substrates and insecticides across cell membranes while detoxifying insecticides, providing atomic-level insights for the development of arthropod pest control agents and strategies for managing pesticide resistance.High-resolution cryo-EM structures and biochemical data reveal the dynamic process by which the ABCH transporter binds and transports lipid substrates and insecticides across cell membranes while detoxifying insecticides, providing atomic-level insights for the development of arthropod pest control agents and strategies for managing pesticide resistance.Jinli Chen, Yanwei Duan, Yuanyuan Zhou, Qing Yanghttps://www.cell.com/cell/fulltext/S0092-8674(24)01375-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 25, 2024
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