Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

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Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signalingWhen extracellular guidance molecules Netrin and RGM that have opposing functions simultaneously bind the Neogenin receptor, a super-complex is formed that diminishes their functional outputs.When extracellular guidance molecules Netrin and RGM that have opposing functions simultaneously bind the Neogenin receptor, a super-complex is formed that diminishes their functional outputs.Ross A. Robinson, Samuel C. Griffiths, Lieke L. van de Haar, Tomas Malinauskas, Eljo Y. van Battum, Pavol Zelina, Rebekka A. Schwab, Dimple Karia, Lina Malinauskaite, Sara Brignani, Marleen H. van den Munkhof, Özge Düdükcü, Anna A. De Ruiter, Dianne M.A. Van den Heuvel, Benjamin Bishop, Jonathan Elegheert, A. Radu Aricescu, R. Jeroen Pasterkamp, Christian Sieboldhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900234-8%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 19, 2021

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