Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopmentHuman accelerated regions (HARs) have been implicated in human brain evolution with limited understanding of the biological processes they alter. This study reports that HARs influenced brain evolution by altering the expression of ancestral gene targets with neurodevelopmental functions shared between human and chimpanzee rather than by gaining new targets in human.Human accelerated regions (HARs) have been implicated in human brain evolution with limited understanding of the biological processes they alter. This study reports that HARs influenced brain evolution by altering the expression of ancestral gene targets with neurodevelopmental functions shared between human and chimpanzee rather than by gaining new targets in human.Atreyo Pal, Mark A. Noble, Matheo Morales, Richik Pal, Marybeth Baumgartner, Je Won Yang, Kristina M. Yim, Severin Uebbing, James P. Noonanhttps://www.cell.com/cell/fulltext/S0092-8674(25)00036-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJanuary 31, 2025

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