Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling

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Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signalingGPCRs signal via localized regions of cAMP that do not mix, leading to action of independent on/off switches rather than coupling via a shared pool of signaling molecules.GPCRs signal via localized regions of cAMP that do not mix, leading to action of independent on/off switches rather than coupling via a shared pool of signaling molecules.Selma E. Anton, Charlotte Kayser, Isabella Maiellaro, Katarina Nemec, Jan Möller, Andreas Koschinski, Manuela Zaccolo, Paolo Annibale, Martin Falcke, Martin J. Lohse, Andreas Bockhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900191-X%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 16, 2022

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