Nutrient-regulated control of lysosome function by signaling lipid conversion

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Nutrient-regulated control of lysosome function by signaling lipid conversionA nutrient-regulated PI(3)P/PI(4)P lipid switch at lysosomes triggers the conversion between motile mTORC1 signaling-active anabolic and static mTORC1 signaling-inactive degradative lysosomes.A nutrient-regulated PI(3)P/PI(4)P lipid switch at lysosomes triggers the conversion between motile mTORC1 signaling-active anabolic and static mTORC1 signaling-inactive degradative lysosomes.Michael Ebner, Dmytro Puchkov, Orestes López-Ortega, Pathma Muthukottiappan, Yanwei Su, Christopher Schmied, Silke Zillmann, Iryna Nikonenko, Jochen Koddebusch, Gillian L. Dornan, Max T. Lucht, Vonda Koka, Wonyul Jang, Philipp Alexander Koch, Alexander Wallroth, Martin Lehmann, Britta Brügger, Mario Pende, Dominic Winter, Volker Hauckehttps://www.cell.com/cell/fulltext/S0092-8674(23)01081-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 26, 2023

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