Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector

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Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effectorCryo-EM and biochemical analyses of a type I-B CAST (CRISPR-associated transposon) provide an improved understanding of various ways in which CAST systems operate; the findings could stimulate ongoing efforts for the development of CASTs as gene knockin tools.Cryo-EM and biochemical analyses of a type I-B CAST (CRISPR-associated transposon) provide an improved understanding of various ways in which CAST systems operate; the findings could stimulate ongoing efforts for the development of CASTs as gene knockin tools.Shukun Wang, Clinton Gabel, Romana Siddique, Thomas Klose, Leifu Changhttps://www.cell.com/cell/fulltext/S0092-8674(23)00743-2?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 9, 2023

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