Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids
Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloidsA stem-cell-derived integrated embryo model recapitulates key post-implantation stages of human development into early organogenesis, including the formation of amniotic and yolk sac cavities, the development of bilaminar and trilaminar discs, the specification of primordial germ cells, the formation of the primitive streak, and gastrulation, as well as the initial stages of neurulation and organogenesis.A stem-cell-derived integrated embryo model recapitulates key post-implantation stages of human development into early organogenesis, including the formation of amniotic and yolk sac cavities, the development of bilaminar and trilaminar discs, the specification of primordial germ cells, the formation of the primitive streak, and gastrulation, as well as the initial stages of neurulation and organogenesis.Lizhong Liu, Seiya Oura, Zachary Markham, James N. Hamilton, Robin M. Skory, Leijie Li, Masahiro Sakurai, Lei Wang, Carlos A. Pinzon-Arteaga, Nicolas Plachta, Gary C. Hon, Jun Wuhttps://www.cell.com/cell/fulltext/S0092-8674(23)00794-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJuly 21, 2023
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