Meningeal lymphatics-microglia axis regulates synaptic physiologyDysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner. Enhancing the function of meningeal lymphatics in aged mice reverses age-associated cognitive and synaptic phenotypes.Dysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner. Enhancing the function of meningeal lymphatics in aged mice reverses age-associated cognitive and synaptic phenotypes.Kyungdeok Kim, Daviti Abramishvili, Siling Du, Zachary Papadopoulos, Jay Cao, Jasmin Herz, Igor Smirnov, Jean-Leon Thomas, Marco Colonna, Jonathan Kipnishttps://www.cell.com/cell/fulltext/S0092-8674(25)00210-7?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 22, 2025

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