Mechanism of gating and partial agonist action in the glycine receptorExamination of the structure and electrophysiological response of the glycine receptor with full and partial agonists reveals agonist-bound closed states as well as open and desensitized states to illuminate conformational states along the receptor reaction pathway and structure-based insights into the mechanism of partial agonist action.Examination of the structure and electrophysiological response of the glycine receptor with full and partial agonists reveals agonist-bound closed states as well as open and desensitized states to illuminate conformational states along the receptor reaction pathway and structure-based insights into the mechanism of partial agonist action.Jie Yu, Hongtao Zhu, Remigijus Lape, Timo Greiner, Juan Du, Wei Lü, Lucia Sivilotti, Eric Gouauxhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900069-6%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 10, 2021

Powered by WPeMatico