Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seqUnbiased, genome-scaling profiling of genetic perturbations via single-cell RNA sequencing enables systematic assignment of function to genes and in-depth study of complex cellular phenotypes such as aneuploidy and stress-specific regulation of the mitochondrial genome.Unbiased, genome-scaling profiling of genetic perturbations via single-cell RNA sequencing enables systematic assignment of function to genes and in-depth study of complex cellular phenotypes such as aneuploidy and stress-specific regulation of the mitochondrial genome.Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson, Jeffrey A. Hussmann, Alexander Lenail, Alina Guna, Lauren Mascibroda, Eric J. Wagner, Karen Adelman, Gila Lithwick-Yanai, Nika Iremadze, Florian Oberstrass, Doron Lipson, Jessica L. Bonnar, Marco Jost, Thomas M. Norman, Jonathan S. Weissmanhttps://www.cell.com/cell/fulltext/S0092-8674(22)00597-9?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJune 10, 2022

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