In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs

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In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugsSun et al. determined the SARS-CoV-2 RNA genome structure in infected cells and from refolded RNAs, which enabled prediction of 42 host proteins that bind to viral RNA using a deep learning tool, and identification of FDA-approved drugs for repurposing to reduce SARS-CoV-2 infection in cells.Sun et al. determined the SARS-CoV-2 RNA genome structure in infected cells and from refolded RNAs, which enabled prediction of 42 host proteins that bind to viral RNA using a deep learning tool, and identification of FDA-approved drugs for repurposing to reduce SARS-CoV-2 infection in cells.Lei Sun, Pan Li, Xiaohui Ju, Jian Rao, Wenze Huang, Lili Ren, Shaojun Zhang, Tuanlin Xiong, Kui Xu, Xiaolin Zhou, Mingli Gong, Eric Miska, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhanghttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900158-6%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 10, 2021

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