Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives SignalingUnlike traditional receptor clustering mediated by intracellular and extracellular domain oligomerization, the transmembrane domain alone of some TNF family receptors can form higher-order structures competent to drive signaling, basally inhibited by the unliganded ectodomain.Unlike traditional receptor clustering mediated by intracellular and extracellular domain oligomerization, the transmembrane domain alone of some TNF family receptors can form higher-order structures competent to drive signaling, basally inhibited by the unliganded ectodomain.Liqiang Pan, Tian-Min Fu, Wenbin Zhao, Linlin Zhao, Wen Chen, Chixiao Qiu, Wenhui Liu, Zhijun Liu, Alessandro Piai, Qingshan Fu, Shuqing Chen, Hao Wu, James J. Chouhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2819%2930150-3%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 1, 2019

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