Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in MiceIn vivo CasRx-mediated downregulation of a single RNA-binding protein, Ptbp1, locally converts glia to neurons and shows promise for treating disorders due to neuronal loss in mice.In vivo CasRx-mediated downregulation of a single RNA-binding protein, Ptbp1, locally converts glia to neurons and shows promise for treating disorders due to neuronal loss in mice.Haibo Zhou, Jinlin Su, Xinde Hu, Changyang Zhou, He Li, Zhaorong Chen, Qingquan Xiao, Bo Wang, Wenyan Wu, Yidi Sun, Yingsi Zhou, Cheng Tang, Fei Liu, Linhan Wang, Canbin Feng, Mingzhe Liu, Sanlan Li, Yifeng Zhang, Huatai Xu, Haishan Yao, Linyu Shi, Hui Yanghttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2930286-5%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 9, 2020

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