Functional and antigenic landscape of the Nipah virus receptor-binding protein

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Functional and antigenic landscape of the Nipah virus receptor-binding proteinNipah virus is a zoonotic virus that spills over to humans and causes infections with a high mortality rate. Deep mutational scanning of the Nipah virus receptor-binding protein provides insights into viral receptor binding and entry into cells as well as antibody escape, thus providing an understanding of viral evolution as well as a roadmap for the design of therapeutics.Nipah virus is a zoonotic virus that spills over to humans and causes infections with a high mortality rate. Deep mutational scanning of the Nipah virus receptor-binding protein provides insights into viral receptor binding and entry into cells as well as antibody escape, thus providing an understanding of viral evolution as well as a roadmap for the design of therapeutics.Brendan B. Larsen, Teagan McMahon, Jack T. Brown, Zhaoqian Wang, Caelan E. Radford, James E. Crowe, David Veesler, Jesse D. Bloomhttps://www.cell.com/cell/fulltext/S0092-8674(25)00257-0?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 25, 2025

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