Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo MethyltransferaseThe pathogenic fungus Cryptococcus neoformans encodes a functional maintenance methyltransferase for 5mC but no de novo enzyme; 5mC has been maintained for millions of years by a combintation of random epimutation and natural selection.The pathogenic fungus Cryptococcus neoformans encodes a functional maintenance methyltransferase for 5mC but no de novo enzyme; 5mC has been maintained for millions of years by a combintation of random epimutation and natural selection.Sandra Catania, Phillip A. Dumesic, Harold Pimentel, Ammar Nasif, Caitlin I. Stoddard, Jordan E. Burke, Jolene K. Diedrich, Sophie Cook, Terrance Shea, Elizabeth Geinger, Robert Lintner, John R. Yates, Petra Hajkova, Geeta J. Narlikar, Christina A. Cuomo, Jonathan K. Pritchard, Hiten D. Madhanihttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2819%2931374-1%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJanuary 17, 2020

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