DNA mutagenesis driven by transcription factor competition with mismatch repair
DNA mutagenesis driven by transcription factor competition with mismatch repairCompetition between transcription factors and mismatch repair machinery drives localized hypermutation at regulatory elements, with implications for cancer and genome evolution.Competition between transcription factors and mismatch repair machinery drives localized hypermutation at regulatory elements, with implications for cancer and genome evolution.Wei Zhu, Yuning Zhang, Harshit Sahay, Hana Wasserman, Ariel Afek, Jonathan Williams, Samantha Shaltz, Caitlin Johnson, Kyle Pinheiro, David M. MacAlpine, Keith R. Weninger, Dorothy A. Erie, Sue Jinks-Robertson, Raluca Gordânhttps://www.cell.com/cell/fulltext/S0092-8674(25)00792-5?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJuly 30, 2025
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