DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs

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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCsAnalysis of primary prostate cancer and circulating tumor cells reveals how DNA hypomethylation during early prostate tumorigenesis silences immune surveillance genes while sparing proliferation-associated genes.Analysis of primary prostate cancer and circulating tumor cells reveals how DNA hypomethylation during early prostate tumorigenesis silences immune surveillance genes while sparing proliferation-associated genes.Hongshan Guo, Joanna A. Vuille, Ben S. Wittner, Emily M. Lachtara, Yu Hou, Maoxuan Lin, Ting Zhao, Ayush T. Raman, Hunter C. Russell, Brittany A. Reeves, Haley M. Pleskow, Chin-Lee Wu, Andreas Gnirke, Alexander Meissner, Jason A. Efstathiou, Richard J. Lee, Mehmet Toner, Martin J. Aryee, Michael S. Lawrence, David T. Miyamoto, Shyamala Maheswaran, Daniel A. Haberhttps://www.cell.com/cell/fulltext/S0092-8674(23)00580-9?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJune 16, 2023

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