Compromised SARS-CoV-2-specific placental antibody transferAtyeo et al. reveals a deficiency in SARS-CoV-2-antibody placental transfer among women infected during the third trimester. While bulk antibody transfer remains unaltered, SARS-CoV-2-antibodies show perturbed Fc glycosylation profiles and elevated IgG and FCGR3A placental expression that suggest compensation for poor transfer.Atyeo et al. reveals a deficiency in SARS-CoV-2-antibody placental transfer among women infected during the third trimester. While bulk antibody transfer remains unaltered, SARS-CoV-2-antibodies show perturbed Fc glycosylation profiles and elevated IgG and FCGR3A placental expression that suggest compensation for poor transfer.Caroline Atyeo, Krista M. Pullen, Evan A. Bordt, Stephanie Fischinger, John Burke, Ashlin Michell, Matthew D. Slein, Carolin Loos, Lydia L. Shook, Adeline A. Boatin, Laura J. Yockey, David Pepin, Marie-Charlotte Meinsohn, Ngoc Minh Phuong Nguyen, Maeva Chauvin, Drucilla Roberts, Ilona T. Goldfarb, Juan D. Matute, Kaitlyn E. James, Lael M. Yonker, Lisa M. Bebell, Anjali J. Kaimal, Kathryn J. Gray, Douglas Lauffenburger, Andrea G. Edlow, Galit Alterhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2931749-9%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 23, 2020

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