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Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor HeteromersThis paper provides a mechanistic understanding of the causes of preeclampsia and uses the newly gained insights to explore treatment for the condition.This paper provides a mechanistic understanding of the causes of preeclampsia and uses the newly gained insights to explore treatment for the condition.Ursula Quitterer, […]

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease ActivityThe cryo-EM structures of Cas12a and smFRET reveal the activation mechanism for target DNA cleavage and indiscriminate ssDNA degradation. The displacement of the R-loop by crRNA suggests a mechanism to stop unspecific ssDNA degradation, resetting the endonuclease to target a new DNA sequence.The cryo-EM structures […]

Boingo gets “significant win” with Metropolitan Transportation Authority dealBoingo to deploy DAS at Grand Central, Jamaica Station and other transit locations In a deal announced Nov. 28, Boingo Wireless said it has worked with New York’s Metropolitan Transportation Authority to secure the wireless rights to outfit two transit facilities with distributed antenna systems and Wi-Fi. […]

Huawei seeks meeting with New Zealand authorities over alleged banNew Zealand telco Spark was not authorized by the government to use Huawei’s 5G gear Chinese vendor Huawei is seeking to establish contacts with New Zealand authorities following yesterday’s announcement that the vendor has been blocked from participating in local carrier Spark’s 5G network deployment, New […]

5G spectrum roundup: Europe Telecom regulators in Europe are accelerating the process to award frequencies for 5G, as operators are expecting to be in a position to launch commercial 5G technology in 2020 in most European markets. Some countries have already awarded initial bands for 5G, while other countries are defining the roadmaps to award […]

Consumers love mobile shopping. Mobile payments? Not so much.Millennials report high adoption and use of smartphone-controlled IoT Nearly half of U.S. shoppers plan to use their smartphones to shop this holiday season, but most of them still haven’t bought into the use of mobile payments applications to pay for purchases, according to a new report […]

3 Hong Kong completes 5G outdoor network trial  The Asian carrier used the 3.5 GHz and 28 GHz spectrum bands for the recent trials   Telecom operator 3 Hong Kong has completed 5G outdoor network trials in the 3.5 GHz and 28 GHz spectrum bands. The carrier said the 5G test was conducted at a […]