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A generative deep learning approach to de novo antibiotic designA generative AI platform is developed for de novo antibiotic design, yielding lead compounds with selective antibacterial activity, distinct mechanisms of action, and in vivo efficacy against multidrug-resistant N. gonorrhoeae and S. aureus.A generative AI platform is developed for de novo antibiotic design, yielding lead compounds […]

Prevalent mesenchymal drift in aging and disease is reversed by partial reprogrammingLoss of cellular identity across aging and disease is linked to a widespread “mesenchymal drift,” characterized by upregulation of mesenchymal genes and altered stromal cell composition across tissues. Mesenchymal drift correlates with worse clinical outcomes, whereas its suppression via Yamanaka factor-induced partial reprogramming restores […]

Inner speech in motor cortex and implications for speech neuroprosthesesInner speech is robustly represented in the motor cortex and can be decoded in real time to restore communication to people with paralysis. Unintentional decoding of private inner speech can be prevented with high fidelity.Inner speech is robustly represented in the motor cortex and can be […]

Cisco: Two billion-dollar orders, with AI infrastructure driving growthCisco delivered strong results for its Q4 and fiscal 2025, and expects a record 2026 driven by AI infrastructure growth In sum — what to know: AI infrastructure orders exceed goal: Cisco had set itself the goal of $1 billion in AI infrastructure order in fiscal 2025 and […]

Huawei Cloud expands global footprintHuawei Cloud now operates across 34 regions and 101 availability zones In sum – what to know: Huawei Cloud’s global scale expands – Now operating in 34 regions and 101 availability zones, serving customers in over 170 countries, with 2024 cloud revenue reaching CNY 68.8 billion. Strong AI ecosystem integration – […]