Assembly Mechanism of Mucin and von Willebrand Factor Polymers

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Assembly Mechanism of Mucin and von Willebrand Factor PolymersJavitt et al. describe molecularly how mucin glycoproteins and von Willebrand factor—complex macromolecules responsible for mucociliary clearance in the lung, the intestinal mucosal barrier, and blood clotting—use a shared mechanism to form polymers and hydrogels that protect the respiratory tract, intestinal tract, and vasculature.Javitt et al. describe molecularly how mucin glycoproteins and von Willebrand factor—complex macromolecules responsible for mucociliary clearance in the lung, the intestinal mucosal barrier, and blood clotting—use a shared mechanism to form polymers and hydrogels that protect the respiratory tract, intestinal tract, and vasculature.Gabriel Javitt, Lev Khmelnitsky, Lis Albert, Lavi Shlomo Bigman, Nadav Elad, David Morgenstern, Tal Ilani, Yaakov Levy, Ron Diskin, Deborah Fasshttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2820%2931162-4%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 8, 2020

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