Archival single-cell genomics reveals persistent subclones during DCIS progression

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Archival single-cell genomics reveals persistent subclones during DCIS progressionArc-well enables reliable high-throughput single-cell genomic sequencing from formalin-fixed paraffin-embedded clinical oncology samples archived for years to decades, and the application of this method reveals genomic features and evolutionary models in ductal carcinoma in situ associated with cancer progression and recurrence.Arc-well enables reliable high-throughput single-cell genomic sequencing from formalin-fixed paraffin-embedded clinical oncology samples archived for years to decades, and the application of this method reveals genomic features and evolutionary models in ductal carcinoma in situ associated with cancer progression and recurrence.Kaile Wang, Tapsi Kumar, Junke Wang, Darlan Conterno Minussi, Emi Sei, Jianzhuo Li, Tuan M. Tran, Aatish Thennavan, Min Hu, Anna K. Casasent, Zhenna Xiao, Shanshan Bai, Lei Yang, Lorraine M. King, Vandna Shah, Petra Kristel, Carolien L. van der Borden, Jeffrey R. Marks, Yuehui Zhao, Amado J. Zurita, Ana Aparicio, Brian Chapin, Jie Ye, Jianjun Zhang, Don L. Gibbons, Grand Challenge PRECISION Consortium, Ellinor Sawyer, Alastair M. Thompson, Andrew Futreal, E. Shelley Hwang, Jelle Wesseling, Esther H. Lips, Nicholas E. Navinhttps://www.cell.com/cell/fulltext/S0092-8674(23)00802-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 16, 2023

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