An inter-organ neural circuit for appetite suppressionLocal actions of the gut peptide GLP-1 are sufficient to cause marked gastric distension and appetite suppression. GLP-1-sensitive ileal neurons connect via abdominal sympathetic ganglia to gastric enteric neurons that cause stomach distension, and stomach volume information is conveyed by the spinal cord to hypothalamic neurons that mediate food rejection.Local actions of the gut peptide GLP-1 are sufficient to cause marked gastric distension and appetite suppression. GLP-1-sensitive ileal neurons connect via abdominal sympathetic ganglia to gastric enteric neurons that cause stomach distension, and stomach volume information is conveyed by the spinal cord to hypothalamic neurons that mediate food rejection.Tong Zhang, Matthew H. Perkins, Hao Chang, Wenfei Han, Ivan E. de Araujohttps://www.cell.com/cell/fulltext/S0092-8674(22)00591-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJune 10, 2022

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