A trans-complementation system for SARS-CoV-2 recapitulates authentic viral replication without virulenceZhang et al. develop a trans-complementation system to produce single-round infectious SARS-CoV-2 that recapitulates authentic viral infection and replication. They then show the system can be safely used at biosafety level-2 for high-throughput antiviral testing.Zhang et al. develop a trans-complementation system to produce single-round infectious SARS-CoV-2 that recapitulates authentic viral infection and replication. They then show the system can be safely used at biosafety level-2 for high-throughput antiviral testing.Xianwen Zhang, Yang Liu, Jianying Liu, Adam L. Bailey, Kenneth S. Plante, Jessica A. Plante, Jing Zou, Hongjie Xia, Nathen E. Bopp, Patricia V. Aguilar, Ping Ren, Vineet D. Menachery, Michael S. Diamond, Scott C. Weaver, Xuping Xie, Pei-Yong Shihttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900233-6%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 24, 2021

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