Mitochondrial activity tunes nociceptor resilience to excitotoxicityExcitation enables neuronal function; however, overexcitation and calcium overload can be deadly. This study reveals a cellular resilience program in which reduced expression of electron transport chain components protects against excitotoxic death, as seen in pain-sensing primary afferent neurons (nociceptors).Excitation enables neuronal function; however, overexcitation and calcium overload can be deadly. This study reveals a cellular resilience program in which reduced expression of electron transport chain components protects against excitotoxic death, as seen in pain-sensing primary afferent neurons (nociceptors).Lin Yuan, Navdeep S. Chandel, David Juliushttps://www.cell.com/cell/fulltext/S0092-8674(25)00914-6?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 27, 2025

Powered by WPeMatico