An alternate receptor for adeno-associated virusesDhungel et al. report an alternate receptor for AAV (AAVR2, carboxypeptidase D), which is distinct from the multi-serotype AAV receptor (AAVR). This study provides insights into AAV biology and clinically deployable solutions to reduce dose-related toxicities associated with AAV vectors.Dhungel et al. report an alternate receptor for AAV (AAVR2, carboxypeptidase D), which is distinct from the multi-serotype AAV receptor (AAVR). This study provides insights into AAV biology and clinically deployable solutions to reduce dose-related toxicities associated with AAV vectors.Bijay P. Dhungel, Hua Xu, Rajini Nagarajah, Joseph Vitale, Alex C.H. Wong, Divya Gokal, Yue Feng, Mehdi Sharifi Tabar, Cynthia Metierre, Chirag Parsania, Xiaohui Song, Guopeng Wang, Xiao-dong Su, Charles G. Bailey, John E.J. Raskohttps://www.cell.com/cell/fulltext/S0092-8674(25)00692-0?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJuly 15, 2025

Powered by WPeMatico