Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction networkSequence and structure-based analysis highlight the molecular principles driving chemokine-GPCR selectivity and promiscuity, enabling the design of chemokines with altered receptor preferences.Sequence and structure-based analysis highlight the molecular principles driving chemokine-GPCR selectivity and promiscuity, enabling the design of chemokines with altered receptor preferences.Andrew B. Kleist, Martyna Szpakowska, Lindsay J. Talbot, Greg Slodkowicz, Duccio Malinverni, Monica A. Thomas, Kyler S. Crawford, Daniel J. McGrail, Acacia F. Dishman, Michael J. Wedemeyer, Madison Sluter, S. Stephen Yi, Nidhi Sahni, Francis C. Peterson, Andy Chevigné, Brian F. Volkman, M. Madan Babuhttps://www.cell.com/cell/fulltext/S0092-8674(25)00398-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 24, 2025
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