Precision proteogenomics reveals pan-cancer impact of germline variantsPrecision proteogenomics analysis of 1,064 cancer patients across ten cancer types unveils the ways in which rare and common germline variants shape the cancer proteome; the findings highlight the contribution of germline genetics in tumor heterogeneity and oncogenesis.Precision proteogenomics analysis of 1,064 cancer patients across ten cancer types unveils the ways in which rare and common germline variants shape the cancer proteome; the findings highlight the contribution of germline genetics in tumor heterogeneity and oncogenesis.Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Kathleen J. Imbach, Karl R. Clauser, Myvizhi Esai Selvan, Isabel Mendizabal, Yifat Geffen, Yo Akiyama, Myranda Maynard, Tomer M. Yaron, Yize Li, Song Cao, Erik P. Storrs, Olivia S. Gonda, Adrian Gaite-Reguero, Akshay Govindan, Emily A. Kawaler, Matthew A. Wyczalkowski, Robert J. Klein, Berk Turhan, Karsten Krug, D.R. Mani, Felipe da Veiga Leprevost, Alexey I. Nesvizhskii, Steven A. Carr, David Fenyö, Michael A. Gillette, Antonio Colaprico, Antonio Iavarone, Ana I. Robles, Kuan-lin Huang, Chandan Kumar-Sinha, François Aguet, Alexander J. Lazar, Lewis C. Cantley, Urko M. Marigorta, Zeynep H. Gümüş, Matthew H. Bailey, Gad Getz, Eduard Porta-Pardo, Li Ding, Clinical Proteomic Tumor Analysis Consortiumhttps://www.cell.com/cell/fulltext/S0092-8674(25)00344-7?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 15, 2025

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