Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution
Neutrophil-derived vesicles control complement activation to facilitate inflammation resolutionShort-lived neutrophils are typically known for their pro-inflammatory role in pathogen clearance. This study highlights the formation of CD55+ LAND-Vs produced from aging neutrophils as a key mechanism for controlling complement activation and resolving inflammation, thereby extending neutrophil functions beyond their usual lifespan.Short-lived neutrophils are typically known for their pro-inflammatory role in pathogen clearance. This study highlights the formation of CD55+ LAND-Vs produced from aging neutrophils as a key mechanism for controlling complement activation and resolving inflammation, thereby extending neutrophil functions beyond their usual lifespan.Alan Y. Hsu, Qingxiang Huang, Xiong Pi, Jianing Fu, Krishnan Raghunathan, Laxman Ghimire, Arumugam Balasubramanian, Xuemei Xie, Hongbo Yu, Fabien Loison, Viraga Haridas, Jiali Zha, Fei Liu, Shin-young Park, Kamal Bagale, Qian Ren, Yuping Fan, Yi Zheng, Jose A. Cancelas, Li Chai, Sean R. Stowell, Kanchao Chen, Rong Xu, Xiaoxue Wang, Yuanfu Xu, Lianghui Zhang, Tao Cheng, Fengxia Ma, Jay R. Thiagarajah, Hao Wu, Sizhou Feng, Hongbo R. Luohttps://www.cell.com/cell/fulltext/S0092-8674(25)00050-9?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignFebruary 12, 2025
Powered by WPeMatico