Proteolethargy is a pathogenic mechanism in chronic disease

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Proteolethargy is a pathogenic mechanism in chronic diseasePathogenic signaling leads to reduced mobility of proteins with diverse functions. This proteolethargy, which is due to increased oxidation of cysteine residues, may account for diverse cellular phenotypes seen in chronic diseases.Pathogenic signaling leads to reduced mobility of proteins with diverse functions. This proteolethargy, which is due to increased oxidation of cysteine residues, may account for diverse cellular phenotypes seen in chronic diseases.Alessandra Dall’Agnese, Ming M. Zheng, Shannon Moreno, Jesse M. Platt, An T. Hoang, Deepti Kannan, Giuseppe Dall’Agnese, Kalon J. Overholt, Ido Sagi, Nancy M. Hannett, Hailey Erb, Olivia Corradin, Arup K. Chakraborty, Tong Ihn Lee, Richard A. Younghttps://www.cell.com/cell/fulltext/S0092-8674(24)01274-1?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignNovember 28, 2024

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