CSF proteomics identifies early changes in autosomal dominant Alzheimer’s diseaseExamination of CSF proteins in mutation carriers and non-carriers for autosomal dominant Alzheimer’s disease uncovers early proteomic changes and generates a robust ADAD prediction model. The findings highlight the similarities and differences between ADAD and sporadic Alzheimer’s disease, which can lead to personalized medicine for mutation carriers in ADAD genes.Examination of CSF proteins in mutation carriers and non-carriers for autosomal dominant Alzheimer’s disease uncovers early proteomic changes and generates a robust ADAD prediction model. The findings highlight the similarities and differences between ADAD and sporadic Alzheimer’s disease, which can lead to personalized medicine for mutation carriers in ADAD genes.Yuanyuan Shen, Jigyasha Timsina, Gyujin Heo, Aleksandra Beric, Muhammad Ali, Ciyang Wang, Chengran Yang, Yueyao Wang, Daniel Western, Menghan Liu, Priyanka Gorijala, John Budde, Anh Do, Haiyan Liu, Brian Gordon, Jorge J. Llibre-Guerra, Nelly Joseph-Mathurin, Richard J. Perrin, Dario Maschi, Tony Wyss-Coray, Pau Pastor, Alan E. Renton, Ezequiel I. Surace, Erik C.B. Johnson, Allan I. Levey, Ignacio Alvarez, Johannes Levin, John M. Ringman, Ricardo Francisco Allegri, Nicholas Seyfried, Gregg S. Day, Qisi Wu, M. Victoria Fernández, Rawan Tarawneh, Eric McDade, John C. Morris, Randall J. Bateman, Alison Goate, Dominantly Inherited Alzheimer Network, Laura Ibanez, Yun Ju Sung, Carlos Cruchagahttps://www.cell.com/cell/fulltext/S0092-8674(24)00978-4?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignSeptember 27, 2024

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