Infant microbes and metabolites point to childhood neurodevelopmental disorders
Infant microbes and metabolites point to childhood neurodevelopmental disordersThis prospective, birth cohort multi-omic study reveals disruptions in the infant gut microbiome associated with later-diagnosed neurodevelopmental disorders. Microbial and metabolomic changes, correlating with risk factors, HLA genetics, and mood/gastrointestinal issues, support the hypothesis of early-life origins of neurodevelopmental disorders, underscoring an important role of gut microbiota.This prospective, birth cohort multi-omic study reveals disruptions in the infant gut microbiome associated with later-diagnosed neurodevelopmental disorders. Microbial and metabolomic changes, correlating with risk factors, HLA genetics, and mood/gastrointestinal issues, support the hypothesis of early-life origins of neurodevelopmental disorders, underscoring an important role of gut microbiota.Angelica P. Ahrens, Tuulia Hyötyläinen, Joseph R. Petrone, Kajsa Igelström, Christian D. George, Timothy J. Garrett, Matej Orešič, Eric W. Triplett, Johnny Ludvigssonhttps://www.cell.com/cell/fulltext/S0092-8674(24)00238-1?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 4, 2024
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