A disordered region controls cBAF activity via condensation and partner recruitmentIntrinsically disordered regions (IDRs), together with the ARID DNA-binding domain of ARID1A/B subunits, dictate cBAF chromatin remodeler complex condensate formation, chromatin localization, and protein-protein interactions, governed by specific IDR sequence grammars.Intrinsically disordered regions (IDRs), together with the ARID DNA-binding domain of ARID1A/B subunits, dictate cBAF chromatin remodeler complex condensate formation, chromatin localization, and protein-protein interactions, governed by specific IDR sequence grammars.Ajinkya Patil, Amy R. Strom, Joao A. Paulo, Clayton K. Collings, Kiersten M. Ruff, Min Kyung Shinn, Akshay Sankar, Kasey S. Cervantes, Tobias Wauer, Jessica D. St. Laurent, Grace Xu, Lindsay A. Becker, Steven P. Gygi, Rohit V. Pappu, Clifford P. Brangwynne, Cigall Kadochhttps://www.cell.com/cell/fulltext/S0092-8674(23)00965-0?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignOctober 3, 2023

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