Humanized mouse liver reveals endothelial control of essential hepatic metabolic functionsA comprehensive human liver tissue was established in a mouse host that consists of all human-relevant parenchymal and non-parenchymal cell types and mimics the cellular composition, histological architecture, and functional properties of a human liver. This highly human-relevant murine model allows investigation of human-specific metabolic features and liver cell type interactions.A comprehensive human liver tissue was established in a mouse host that consists of all human-relevant parenchymal and non-parenchymal cell types and mimics the cellular composition, histological architecture, and functional properties of a human liver. This highly human-relevant murine model allows investigation of human-specific metabolic features and liver cell type interactions.Eleanna Kaffe, Manolis Roulis, Jun Zhao, Rihao Qu, Esen Sefik, Haris Mirza, Jing Zhou, Yunjiang Zheng, Georgia Charkoftaki, Vasilis Vasiliou, Daniel F. Vatner, Wajahat Z. Mehal, AlcHepNet, Yuval Kluger, Richard A. Flavellhttps://www.cell.com/cell/fulltext/S0092-8674(23)00795-X?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 10, 2023

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