Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneityVaccine boosting modifies CAR T cell metabolism and promotes crosstalk between CAR T cells and endogenous immunity to elicit and sustain antigen spreading, thereby effectively treating tumors with antigen heterogeneity.Vaccine boosting modifies CAR T cell metabolism and promotes crosstalk between CAR T cells and endogenous immunity to elicit and sustain antigen spreading, thereby effectively treating tumors with antigen heterogeneity.Leyuan Ma, Alexander Hostetler, Duncan M. Morgan, Laura Maiorino, Ina Sulkaj, Charles A. Whittaker, Alexandra Neeser, Ivan Susin Pires, Parisa Yousefpour, Justin Gregory, Kashif Qureshi, Jonathan Dye, Wuhbet Abraham, Heikyung Suh, Na Li, J. Christopher Love, Darrell J. Irvinehttps://www.cell.com/cell/fulltext/S0092-8674(23)00642-6?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJuly 6, 2023

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