Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicityCoordinated interaction of the ZBP1 and cGAS pathways ties the sensing of mitochondrial Z-DNA to type I interferon signaling and cardiac damage.Coordinated interaction of the ZBP1 and cGAS pathways ties the sensing of mitochondrial Z-DNA to type I interferon signaling and cardiac damage.Yuanjiu Lei, Jordyn J. VanPortfliet, Yi-Fan Chen, Joshua D. Bryant, Ying Li, Danielle Fails, Sylvia Torres-Odio, Katherine B. Ragan, Jingti Deng, Armaan Mohan, Bing Wang, Olivia N. Brahms, Shawn D. Yates, Michael Spencer, Carl W. Tong, Marcus W. Bosenberg, Laura Ciaccia West, Gerald S. Shadel, Timothy E. Shutt, Jason W. Upton, Pingwei Li, A. Phillip Westhttps://www.cell.com/cell/fulltext/S0092-8674(23)00591-3?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignJune 23, 2023
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