Repeat-based holocentromeres influence genome architecture and karyotype evolutionWhile most eukaryotes contain single regional centromeres, several plant and animal lineages assemble holocentromeres along the entire chromosome length. The assembly of chromosome-scale holocentric genomes with repeat-based holocentromeres from beak-sedges and their closest monocentric relative sheds light on important aspects of genome architecture and evolution influenced by centromere organization.While most eukaryotes contain single regional centromeres, several plant and animal lineages assemble holocentromeres along the entire chromosome length. The assembly of chromosome-scale holocentric genomes with repeat-based holocentromeres from beak-sedges and their closest monocentric relative sheds light on important aspects of genome architecture and evolution influenced by centromere organization.Paulo G. Hofstatter, Gokilavani Thangavel, Thomas Lux, Pavel Neumann, Tihana Vondrak, Petr Novak, Meng Zhang, Lucas Costa, Marco Castellani, Alison Scott, Helena Toegelová, Joerg Fuchs, Yennifer Mata-Sucre, Yhanndra Dias, André L.L. Vanzela, Bruno Huettel, Cicero C.S. Almeida, Hana Šimková, Gustavo Souza, Andrea Pedrosa-Harand, Jiri Macas, Klaus F.X. Mayer, Andreas Houben, André Marqueshttps://www.cell.com/cell/fulltext/S0092-8674(22)00797-8?rss=yeshttp://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignAugust 4, 2022

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