Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

By admin In News, Technology, Wireless Cell Telecom No comments

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccineImmunization with 2 doses of mRNA vaccine encoding the ancestral SARS-CoV-2 spike protein induces a population of durable memory B cells with broad reactivity to viral variants including omicron. Boosting with a 3rd dose of ancestral vaccine increases neutralizing antibody levels, thus highlighting the significance of vaccine-induced B cell memory.Immunization with 2 doses of mRNA vaccine encoding the ancestral SARS-CoV-2 spike protein induces a population of durable memory B cells with broad reactivity to viral variants including omicron. Boosting with a 3rd dose of ancestral vaccine increases neutralizing antibody levels, thus highlighting the significance of vaccine-induced B cell memory.Rishi R. Goel, Mark M. Painter, Kendall A. Lundgreen, Sokratis A. Apostolidis, Amy E. Baxter, Josephine R. Giles, Divij Mathew, Ajinkya Pattekar, Arnold Reynaldi, David S. Khoury, Sigrid Gouma, Philip Hicks, Sarah Dysinger, Amanda Hicks, Harsh Sharma, Sarah Herring, Scott Korte, Wumesh KC, Derek A. Oldridge, Rachel I. Erickson, Madison E. Weirick, Christopher M. McAllister, Moses Awofolaju, Nicole Tanenbaum, Jeanette Dougherty, Sherea Long, Kurt D’Andrea, Jacob T. Hamilton, Maura McLaughlin, Justine C. Williams, Sharon Adamski, Oliva Kuthuru, Elizabeth M. Drapeau, Miles P. Davenport, Scott E. Hensley, Paul Bates, Allison R. Greenplate, E. John Wherryhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900456-1%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 8, 2022

Powered by WPeMatico