Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome

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Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiomeA computational and experimental strategy was developed to redesign biosynthetic gene clusters into synthetic genetic elements that can be expressed across a wide range of prokaryote and eukaryote hosts, expanding our ability to discover and characterize a variety of natural products and biosynthetic pathways.A computational and experimental strategy was developed to redesign biosynthetic gene clusters into synthetic genetic elements that can be expressed across a wide range of prokaryote and eukaryote hosts, expanding our ability to discover and characterize a variety of natural products and biosynthetic pathways.Jaymin R. Patel, Joonseok Oh, Shenqi Wang, Jason M. Crawford, Farren J. Isaacshttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900268-9%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignApril 2, 2022

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