Spatial CRISPR genomics identifies regulators of the tumor microenvironment

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Spatial CRISPR genomics identifies regulators of the tumor microenvironmentA spatial functional genomics platform termed Perturb-map combines CRISPR pools, multiplex imaging, and spatial transcriptomics to enable the identification of genetic determinants of tumor composition, organization, and immunity.A spatial functional genomics platform termed Perturb-map combines CRISPR pools, multiplex imaging, and spatial transcriptomics to enable the identification of genetic determinants of tumor composition, organization, and immunity.Maxime Dhainaut, Samuel A. Rose, Guray Akturk, Aleksandra Wroblewska, Sebastian R. Nielsen, Eun Sook Park, Mark Buckup, Vladimir Roudko, Luisanna Pia, Robert Sweeney, Jessica Le Berichel, C. Matthias Wilk, Anela Bektesevic, Brian H. Lee, Nina Bhardwaj, Adeeb H. Rahman, Alessia Baccarini, Sacha Gnjatic, Dana Pe’er, Miriam Merad, Brian D. Brownhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2822%2900195-7%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMarch 15, 2022

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