NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activationFormation of a membrane-bound, double-ring cage structure controls activation of the murine NLRP3 protein, thus clarifying the native oligomeric form in cells and the structural basis of the early activation steps leading to inflammasome assembly and IL-1-family cytokine processing.Formation of a membrane-bound, double-ring cage structure controls activation of the murine NLRP3 protein, thus clarifying the native oligomeric form in cells and the structural basis of the early activation steps leading to inflammasome assembly and IL-1-family cytokine processing.Liudmila Andreeva, Liron David, Shaun Rawson, Chen Shen, Teerithveen Pasricha, Pablo Pelegrin, Hao Wuhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2901326-X%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignDecember 3, 2021

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