Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair

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Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repairCo-injection of mouse zygotes with RAD51 and Cas9 can enhance interhomolog repair and facilitate conversion of heterozygous alleles to homozygous alleles.Co-injection of mouse zygotes with RAD51 and Cas9 can enhance interhomolog repair and facilitate conversion of heterozygous alleles to homozygous alleles.Jonathan J. Wilde, Tomomi Aida, Ricardo C.H. del Rosario, Tobias Kaiser, Peimin Qi, Martin Wienisch, Qiangge Zhang, Steven Colvin, Guoping Fenghttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900538-9%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMay 27, 2021

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