Parental genome unification is highly error-prone in mammalian embryosIn human and bovine zygotes, parental genomes cluster and polarize toward each other in a highly error-prone process driven by centrosomes, dynein, microtubules, and nuclear pore complexes. Failure to cluster the parental genomes leads to chromosome segregation errors and micronuclei, which are incompatible with healthy embryo development.In human and bovine zygotes, parental genomes cluster and polarize toward each other in a highly error-prone process driven by centrosomes, dynein, microtubules, and nuclear pore complexes. Failure to cluster the parental genomes leads to chromosome segregation errors and micronuclei, which are incompatible with healthy embryo development.Tommaso Cavazza, Yuko Takeda, Antonio Z. Politi, Magomet Aushev, Patrick Aldag, Clara Baker, Meenakshi Choudhary, Jonas Bucevičius, Gražvydas Lukinavičius, Kay Elder, Martyn Blayney, Andrea Lucas-Hahn, Heiner Niemann, Mary Herbert, Melina Schuhhttps://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=https%3A%2F%2Fwww.cell.com%2Fcell%2Ffulltext%2FS0092-8674%2821%2900492-X%3Frss%3Dyes&rc=0http://www.cell.com/cell/inpress.rssCellCell RSS feed.Wireless News CampaignMay 8, 2021

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